CRO Finder

Hit-to-Lead Optimization CROs

Systematic refinement of initial screening hits into viable lead compounds through medicinal chemistry and SAR analysis.

32 organizations offer this service

WuXi AppTec

Featured
Shanghai, China Full Service

Leading global pharmaceutical and medical device open-access capability and technology platform. WuXi AppTec provides services spanning from discovery through manufacturing across small molecules, biologics, and cell/gene therapies.

GLP GMP AAALAC ISO 9001

Medicilon

Shanghai, China Full Service

Chinese integrated drug discovery and development CRO providing medicinal chemistry, ADME/PK, pharmacology, toxicology, and CMC services from Shanghai operations.

GLP GMP AAALAC ISO 9001

Pharmaron

Beijing, China Full Service

Integrated pharmaceutical R&D service platform offering drug discovery, preclinical, clinical, and commercial manufacturing services to biotech and pharma companies globally.

GLP GMP AAALAC FDA Registered

Evotec

Hamburg, Germany Specialty

Drug discovery and development company offering a range of discovery and preclinical services including target validation, hit identification, lead optimization, and ADME/PK.

GLP ISO 9001

Reaction Biology

Malvern, PA, USA Specialty

Specialty CRO providing biochemical and cell-based assay services for drug discovery. Known for kinase profiling, epigenetic screening, and custom assay development.

ISO 9001

Nuvisan

Neu-Ulm, Germany Full Service

Fully integrated German CRO/CDMO offering drug discovery, non-clinical studies, pharmaceutical analysis, GMP manufacturing, and early-phase clinical trials from facilities in Germany and France.

GLP GMP GCP Compliant ISO 9001

Eurofins Panlabs Discovery

Toulouse, France Testing Lab

Eurofins Discovery division providing high-throughput in-vitro pharmacology screening, compound profiling, ADME assays, and bioanalytical services supporting drug discovery from target identification through lead optimization.

GLP ISO 9001 ISO 17025

Southern Research

Birmingham, AL, USA Specialty

Nonprofit research organization providing drug discovery, preclinical development, and analytical services with deep expertise in oncology and infectious disease including BSL-3 capabilities.

GLP AAALAC FDA Registered

BioDuro-Sundia

San Diego, CA, USA Full Service

Global CRO/CDMO providing integrated drug discovery and development services including medicinal chemistry, ADME/PK, pharmacology, and process chemistry from US and China operations.

GLP GMP ISO 9001

Viva Biotech

Shanghai, China Specialty

Chinese CRO/CDMO providing integrated drug discovery services including structure-based drug design, medicinal chemistry, ADME/PK studies, and biologics development from Shanghai operations.

GLP ISO 9001

Syngene International

Bangalore, India Full Service

Indian integrated research, development, and manufacturing services company serving pharma, biotech, and nutrition companies with discovery chemistry, biology, and manufacturing capabilities.

GLP GMP AAALAC ISO 9001

GVK Biosciences

Hyderabad, India Full Service

Indian research services company providing medicinal chemistry, computational chemistry, biology, DMPK, and clinical development services for global pharma and biotech companies.

GLP GCP Compliant ISO 9001

Jubilant Biosys

Bangalore, India Full Service

Integrated drug discovery and development services company providing medicinal chemistry, ADME/DMPK, pharmacology, and clinical research from India, US, and China operations.

GLP GMP ISO 9001

AMRI Global

Albany, NY, USA CDMO

Contract research and manufacturing organization offering drug discovery, API synthesis, analytical development, and formulation services to global pharma and biotech.

GMP GLP FDA Registered ISO 9001

Aragen Life Sciences

Hyderabad, India Full Service

Hyderabad-headquartered integrated CRDMO providing CRO and CDMO solutions for small and large molecules to 450+ global pharma and biotech clients with 3,000+ professionals.

GLP GMP GCP Compliant ISO 9001

ChemPartner

Shanghai, China Specialty

Shanghai-headquartered CRO/CDMO offering integrated drug discovery chemistry, biology, and biologics development services including ADC and recombinant protein production.

GLP GMP ISO 9001

Fidelta (now Selvita)

Zagreb, Croatia Specialty

Croatian integrated drug discovery CRO providing medicinal chemistry, biology, DMPK, and preclinical development services, now part of Polish CRO Selvita Group.

GLP ISO 9001

Suven Life Sciences

Hyderabad, India Specialty

Hyderabad-headquartered pharmaceutical CRO with dedicated clinical trials division providing drug discovery, early-phase clinical, and regulatory support with strong CNS expertise.

GCP Compliant GLP

Ricerca Biosciences (Olon Ricerca)

Concord, OH, USA CDMO

Contract research organization providing discovery, preclinical, and development chemistry services including API synthesis, safety pharmacology, and medicinal chemistry.

GLP GMP FDA Registered

Selvita Group

Krakow, Poland Specialty

Polish integrated drug discovery CRO providing medicinal chemistry, biology, DMPK, computational chemistry, and preclinical services with 1,000+ scientists across Europe.

GLP ISO 9001

Novascreen Biosciences Corp

Hanover, MD, USA Specialty

Hanover, Maryland-based drug screening CRO offering high-throughput receptor binding, enzyme inhibition, and functional cell-based assays for hit-to-lead optimisation programmes.

GLP Compliant

Aptuit Verona

Verona, Italy Full Service

Verona, Italy-based integrated drug discovery and development centre providing medicinal chemistry, DMPK, safety assessment, and pharmaceutical development under the Evotec umbrella.

GLP Compliant GMP Certified

ShangPharma

Shanghai, China Specialty

One of China's earliest chemistry-focused CROs offering integrated drug discovery, DMPK, and pharmaceutical development services globally.

GLP Compliant ISO 9001

Hande Biotech

Suzhou, China Specialty

Chinese CRO and CDMO offering integrated preclinical biology, in-vitro pharmacology, and early drug discovery services for domestic and multinational pharma clients.

ISO 9001 GLP Compliant

Bellen Chemistry

Dalian, China CDMO

Chinese CDMO specializing in custom synthesis of building blocks, advanced intermediates, and reference compounds for global pharmaceutical R&D, with a catalog of over 40,000 compounds.

ISO 9001 ISO 14001

Fidelta Croatia

Zagreb, Croatia Specialty

Zagreb-based drug discovery CRO (Selvita Group) providing integrated medicinal chemistry, ADME/PK, and in vitro biology services for hit-to-lead and lead optimization programs.

GLP Compliant ISO 9001

Sai Life Sciences

Hyderabad, India CDMO

Hyderabad-based Indian CDMO providing integrated drug discovery, development, and manufacturing services with capabilities spanning medicinal chemistry through commercial API supply.

GMP Compliant ISO 9001 FDA Inspected

GVK Bio Discovery

Hyderabad, India Full Service

Hyderabad-based Indian CRO providing contract research in discovery chemistry, biology, DMPK, and clinical development with integrated data analytics platform GOSTAR.

GLP Compliant GCP Compliant

BioDuro-Sundia Shanghai

Shanghai, China Full Service

Shanghai campus of BioDuro-Sundia providing integrated discovery and development services including medicinal chemistry, DMPK, biology, and preclinical development for global biotech.

GLP Compliant GMP Compliant

Oncodesign Services

Dijon, France Specialty

European preclinical CRO in Dijon, France, specializing in oncology, inflammation, and infectious disease drug discovery including targeted radiotherapy programs.

GLP Compliant ISO 9001

Aurigene Pharmaceutical Services

Hyderabad, India CDMO

Dr. Reddy's wholly-owned integrated CRO and CDMO for small molecules and biologics, combining 650+ Indian scientists with GMP manufacturing in the UK, Mexico, and India.

GLP Compliant GMP Compliant ISO 9001

Mosaic Biosciences

Boulder, CO, USA Specialty

Boulder-based biologic discovery CRO integrating antibody discovery, protein engineering, function-first screening, and early developability assessment for complex biotherapeutics.

ISO 9001